Wednesday, November 13, 2019

Gene Therapy Essay -- Biology Medical Biomedical Genetics

Gene Therapy: The New Vaccine ABSTRACT This research paper details what gene therapy is and what it is (and potentially will be) used for. It also describes the gene therapy techniques and delivery methods that have been clinically tested and/or verified by scientists and the ideas that stimulate activity in the field in the race to perfect gene therapy methods and their application, as well as telling about the beginnings of its clinical testing and where this budding technology is headed. Finally, it discusses one last question: Is gene therapy the vaccination of the future? RESEARCH Gene therapy is a biotechnological technique that has recently made significant leaps of progress in the world of scientific research. The theories behind its use have created many new goals and ideas in scientists’ minds, and there is much opportunity for discovery in the field. There are two types of genetic technology that are currently being researched for application in clinical testing and for the cure of certain genetic diseases in humans: somatic cell gene therapy, and germ-line therapy. Somatic cell gene therapy is a development that could potentially eliminate a hereditary disease’s effects in a patient through the injection of genetic material that would fill in for a nonfunctional gene, alter an abnormal one in the patient’s chromosomes, or exchange the defective gene for a new, fully-functioning one (www.ornl.org). Germ-line therapy would be used similarly in embryos’ germ cells, but would have the additional effect of the faulty gene’s permanent eradication so that it could not be passed on to future descendants. There are also multiple types of somatic cell gene therapy. In vivo gene therapy, the most common in clinical testin... ...entists will make many revolutionary discoveries. With this new technology being researched, there’s no telling when the technology will be perfected. Who knows? Someday soon, gene therapy could even be something as commonplace as vaccination. Bibliography: 6 Friedmann, The Development of Human Gene Therapy http://www.ornl.gov/sci/techresources/Human_Genome/medicine/genetherapy.shtml http://www.accessexcellence.org/RC/AB/BA/Gene_Therapy_Overview.html http://asgt.org/news_releases/basics.html http://www.fda.gov/fdac/features/2000/500_gene.html http://www.cancer.gov/cancertopics/factsheet/Therapy/gene (G.T. for Cancer) http://content.nejm.org/cgi/content/short/346/16/1185 (Ex Vivo for X-SCID) http://asgt.org/news_releases/06022005a.html http://genome.gov/13014325 Reilly, Abraham Lincoln’s DNA and Other Adventures in Genetics Turksen, Adult Stem Cells 7

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